CXCL12 targets the primary cilium cAMP/cGMP ratio to regulate cell polarity during migration
Abstract Directed cell migration requires sustained cell polarisation.In migrating cortical interneurons, nuclear Ski de fond - Equipement - Skis - Skate movements are directed towards the centrosome that organises the primary cilium signalling hub.Primary cilium-elicited signalling, and how it affects migration, remain however ill characterised.He